About YUVEZZI
YUVEZZI is a prescription eye drop for adults with blurry close-up vision due to age, a condition known as “presbyopia.”
Yes, YUVEZZI is available only with a prescription. Eye doctors such as optometrists and ophthalmologists can prescribe YUVEZZI. Find an eye doctor near you.
YUVEZZI eye drops combine two active ingredients that work together to improve close-up vision:
- The first active ingredient, called “carbachol,” helps your pupils get smaller, making it easier to focus up close
- The second ingredient, called “brimonidine” helps keep your pupils from getting too large
Both active ingredients in YUVEZZI have been trusted to treat other common eye conditions for nearly 30 years.
In medical studies, YUVEZZI was shown to work in as little as 30 minutes for some patients. Learn more about results with YUVEZZI.
In medical studies, YUVEZZI provided up to 8 continuous hours of improved close-up vision. About half of patients could read up close at “hour 8.” Hear what patients have to say about YUVEZZI.
No; in medical studies, after 1 year of use, YUVEZZI consistently improved blurry close-up vision like it did at the start.
No, YUVEZZI helps you see up close without affecting your distance vision. In medical studies, patients taking YUVEZZI were able to read at least 3 more lines on an eye chart in low light without losing distance vision, compared to before using YUVEZZI. Learn more about results with YUVEZZI.
The active ingredients of YUVEZZI are carbachol and brimonidine. Carbachol helps your pupils get smaller, making it easier to focus up close. Brimonidine helps keep your pupils from getting too large. Both ingredients have been used to treat other common eye conditions for nearly 30 years. The inactive ingredients of YUVEZZI are: hydroxypropyl methylcellulose (HPMC), sodium phosphate monobasic monohydrate, sodium phosphate dibasic heptahydrate, water for injection, and may also include hydrochloric acid and/or sodium hydroxide.
No, YUVEZZI is preservative free.
YUVEZZI was developed by Tenpoint Therapeutics, an eye care company dedicated to rejuvenating vision for people with aging eyes.
YUVEZZI Cost and Coverage
The price of YUVEZZI is $79 for 30-day supply and $198 for 90-day supply ($66 per month). These prices are available through PhilRx, the e-Pharmacy, or at your local retail pharmacy. As prices may vary across retail pharmacies, download our savings card to get the best price. And don’t forget to sign up for exclusive offers and updates!
No, YUVEZZI is not covered by insurance, so you can skip the hassle. You can use your Health Savings Account (HSA) or Flexible Spending Account (FSA) to pay for YUVEZZI.
No, YUVEZZI is not covered Medicare. If you have a Health Savings Account (HSA) or Flexible Spending Account (FSA), you can use either of these to pay for YUVEZZI.
Using YUVEZZI
To use YUVEZZI, twist off the top of the plastic vial and squeeze the vial to release 1 drop in each eye. Throw away the vial, even if it’s not empty. Be careful not to let the tip of the vial touch your eye, eyelid, or any other surface. Watch this video to learn more about how to use YUVEZZI.
Yes, you can use YUVEZZI with contact lenses. Be sure to remove your contacts before using YUVEZZI and wait at least 10 minutes after using YUVEZZI before you put them back in your eyes.
Yes, you can use YUVEZZI instead of reading glasses or with glasses that you use for distance vision.
YUVEZZI can be used every day: one drop per eye, once a day.
Yes, YUVEZZI can be used with other eye drops. If you use another eye drop in addition to YUVEZZI, allow at least 5 minutes between them. Talk to your eye doctor about which drop you should use first.
Yes, if you had LASIK surgery to correct distance or near vision in the past, you could still use YUVEZZI. Ask your eye doctor if YUVEZZI is right for your situation, or find an eye doctor.
No, YUVEZZI does not need to be refrigerated. Store any unused vials in their original foil pouch until ready to use. This protects the vials from light.
Side Effects & Safety
The most common side effects of YUVEZZI seen in the medical studies were: headache, impaired vision, and eye pain and/or eye irritation upon use. Most side effects were generally mild, didn’t last long, and went away on their own.
- Headache rates were generally low (16% of patients) and decreased with continued use
- Eye irritation was experienced by 14% of patients immediately upon use of YUVEZZI, but soon went away
- Eye pain was experienced by 7% of patients immediately upon use of YUVEZZI, but soon went away
- Impaired vision was experienced by 6% of patients
- People taking YUVEZZI had no treatment-related serious side effects in a 1-year safety study, and nearly 9 out of 10 people were able to keep using YUVEZZI without stopping because of side effects for the full year of the study
These are not all the possible side effects of YUVEZZI. Learn more about safety and see the Brief Summary for more information.
Eye redness was not a common side effect in medical studies of YUVEZZI. Fewer than 3 out of 100 people taking YUVEZZI reported eye redness (or “hyperemia”) as a side effect in medical studies.
- Before prescribing YUVEZZI, your eye doctor is advised to check your retina (a layer of cells at the back of your eye that senses light)
- You should not use YUVEZZI if you are allergic to any of the ingredients. Please see the Brief Summary for a list of ingredients
- Before using YUVEZZI, tell your doctor if you currently have inflammation of the iris (a condition called “iritis”), depression, low blood pressure, or circulation problems
- YUVEZZI may cause temporary blurry, dim, or dark vision. If you experience this, you should avoid driving (especially at night), using machinery, and participating in hazardous activities
- Call your doctor right away if you suddenly have flashes of light, floaters, or vision loss
- When using YUVEZZI, do not let the tip of the single-use vial touch your eye, eyelid, or any other surface
Learn more about side effects and see the Brief Summary for more information.
Medicines that have known potential interactions with YUVEZZI are:
- Antihypertensives, which are a type of drug that lowers blood pressure
- Cardiac glycosides, which are a type of drug used to treat certain heart conditions, including heart failure and atrial fibrillation
- CNS depressants including alcohol, opiates, barbiturates, sedatives, or anesthetics
- Tricyclic antidepressants, which are a type of drug used to treat depression, nerve pain, insomnia, and anxiety
- Monoamine oxidase (MAO) inhibitors, which are a type of antidepressant
Be sure to tell your eye doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, dietary and herbal supplements.
Do not use YUVEZZI if you currently have inflammation of the iris (iritis) or if you are allergic to any of its ingredients. See the Brief Summary for a complete list of ingredients.
Getting YUVEZZI
An eye doctor such as an optometrist or ophthalmologist can help decide if YUVEZZI is right for you and write a prescription. Once you have a prescription, you can have YUVEZZI shipped directly to your door through PHIL, the e-Pharmacy, or you can pick it up at your local retail pharmacy.
No, you cannot buy YUVEZZI over the counter because it requires a prescription. Eye doctors such as optometrists and ophthalmologists can prescribe YUVEZZI. Find an eye doctor near you.
Yes, eye doctors including optometrists can prescribe YUVEZZI. Find an eye doctor near you.
About Presbyopia
Presbyopia – or blurry close-up vision due to age – is one of the causes of blurry vision close up. It is a condition that may happen as you get older.
Presbyopia is a common change in vision that makes it harder to see close-up objects clearly as you age.
Presbyopia is caused by changes in the eye due to aging. Over time, the lens in your eye stiffens, making it harder to focus up close. Less common causes of presbyopia can include certain health conditions, some medicines, and eye injury or surgery.
The meaning of the word “presbyopia” has ancient roots in Greek—“presbys” for aging and “opia” for vision. Presbyopia is blurry close-up vision due to aging.
Presbyopia is pronounced PREZ-bee-OH-pee-uh
For most people, presbyopia starts around age 40. According to the American Optometric Association, about 9 out of 10 adults over the age of 45 have presbyopia.
Yes, presbyopia can get worse with age, although it depends on the person. For some people, presbyopia may stop getting worse after a few years. For others, it may worsen into their late 60s or beyond.
Yes, there are several ways to correct presbyopia, which include:
- Glasses, such as reading glasses, bifocals, or progressive lenses
- Multifocal contacts or monovision contacts
- Surgical procedures to reshape the eye or replace the lens
- Prescription presbyopia eye drops, such as YUVEZZI
Yes, a procedure called “Monovision LASIK” is a laser eye surgery that can correct presbyopia in one eye. Usually this surgery involves correcting the dominant eye for distance and the non-dominant eye for close-up vision. However, prescription eye drops, such as YUVEZZI, are a less invasive step you can take instead of surgery.
